Anesthetized pigs underwent full thickness circumferential resection of the mid-lower thoracic esophagus followed by implantation of the cell seeded scaffold. Animals underwent adipose tissue biopsy to harvest and expand autologous aMSCs for seeding on electro-spun polyurethane conduits in a bioreactor. The scaffolds were not incorporated into the regrown esophageal tissue and were retrieved endoscopically. In the current study, we demonstrate that regeneration of esophageal tissue is feasible and reproducible in a large animal model using synthetic polyurethane electro-spun grafts seeded with autologous adipose-derived mesenchymal stem cells (aMSCs) and a disposable bioreactor. A tissue engineered construct providing an alternative for esophageal replacement in circumferential, full thickness resection would have significant clinical applications. Current reconstruction approaches are limited to utilization of an autologous conduit such as stomach, small bowel, or colon. The original information is on Zdziarski's blog.Treatment of esophageal disease can necessitate resection and reconstruction of the esophagus. It would be nice if there were some fully reliable way to ensure that all personal data is expunged from the device. With the 3G iPhone presumably about to drop it seems safe to assume a lot of second-hand iPhones are about to become available on eBay, etc. What's needed is a low-level format of the NAND, but there doesn't seem to be a readily available means for doing this. A detective from the Oregon State police recovered email, photos, and other user data from an "out-of-the-box refurbished iPhone." Indeed the image to the right is a partial screen capture from the refurbished iPhone.Īccording to the iPhone developer Jonathan Zdziarski "all of the personal information that was sitting on prior to the erase or restore is still left sitting in the unallocated blocks of the iPhone's NAND memory." In other words doing a Restore operation through iTunes will not actually fully delete all the data on the iPhone. Apparently user data is recoverable from iPhones that are being sold as refurbished. Here's a slightly disturbing story from iPhone Atlas.
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